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Proteintech
E2F8 Polyclonal Antibody
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产品信息
13425-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E2F8 Fusion Protein Ag4216 (78-508 aa encoded by BC028244)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MAQLAAICK MQLEEQSSES RQKVKVQLAR SGPCKPVAPL DPPVNAEMEL TAPSLIQPLG MVPLIPSPLS SAVPLILPQA PSGPSYAIYL QPTQAHQSVT PPQGLSPTVC TTHSSKATGS KDSTDATTEK AANDTSKASA STRPGSLLPA PERQGAKSRT REPAGERGSK RASMLEDSGS KKKFKEDLKG LENVSATLFP SGYLIPLTQC SSLGAESILS GKENSSALSP NHRIYSSPIA GVIPVTSSEL TAVNFPSFHV TPLKLMVSPT SVAAVPVGNS PALASSHPVP IQNPSSAIVN FTLQHLGLIS PNVQLSASPG SGIVPVSPRI ESVNVAPENA GTQQGRATNY DSPVPGQSQP NGQSVAVTGA QQPVPVTPKG SQLVAESFFR TPGGPTKPTS SSCMDFEGAN KTSLGTLFVP QRKLEVSTED VH (78-508 aa encoded by BC028244)
靶标信息
E2F transcription factors, such as E2F8, are essential for orchestrating expression of genes required for cell cycle progression and proliferation (Christensen et al., 2005).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: E2F 8; E2F family member 8; E2F-8; FLJ23311; Transcription factor E2F8
基因别名: E2F-8; E2F8
UniProt ID: (Human) A0AVK6
Entrez Gene ID: (Human) 79733
RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
protein homodimerization activity
RNA metabolism protein
nucleic acid metabolism protein
general transcription factor
negative regulation of transcription from RNA polymerase II promoter
placenta development
sprouting angiogenesis
transcription, DNA-templated
cell proliferation
negative regulation of cytokinesis
positive regulation of DNA endoreduplication
cell cycle comprising mitosis without cytokinesis
positive regulation of transcription from RNA polymerase II promoter
trophoblast giant cell differentiation
chorionic trophoblast cell differentiation
hepatocyte differentiation
