应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:500-1:5,000 | - |
免疫组化(石蜡) (IHC (P)) |
1:200-1:500 | - |
酶联免疫吸附实验 (ELISA) |
Assay-Dependent | - |
产品规格 | |
---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant Human E2F-associated phosphoprotein protein (1-285AA) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
4 mg/mL |
纯化类型 |
Protein G |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.03% Proclin 300 |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2812298 |
This protein may play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The C-terminal of EAPP binds the N-terminal of E2F1 and also interacts with E2F2 and E2F3, but not E2F4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E2F-associated phosphoprotein; EAPP
基因别名: BM-036; BM036; C14orf11; EAPP
UniProt ID: (Human) Q56P03
Entrez Gene ID: (Human) 55837