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PA1-23557 detects Lysophosphatidic Acid Receptor 2 in Human samples.
PA1-23557 has been successfully used in Immunohistochemistry (Paraffin) procedures.
PA1-23557 immunogen corresponds to Synthetic peptide - KLH conjugated.
Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion. Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. Edg4 expression has also been seen in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。