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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000 | - |
免疫细胞化学 (ICC/IF) |
1:100 | - |
免疫沉淀 (IP) |
1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Non-human primate, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide corresponding to residues surrounding the N-terminus of human eEF2k |
偶联物 |
Unconjugated |
形式 |
Liquid |
纯化类型 |
Antigen affinity chromatography |
保存液 |
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
内含物 |
no preservative |
保存条件 |
-20°C |
RRID |
AB_10981348 |
It is not recommended to aliquot this antibody.
EEF2K (eukaryotic elongation factor 2 kinase) is a threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Up activation, by a variety of upstream kinases including AMPK or TRPM7, EEF2K phosphorylates the elongation factor EEF2 at a single site. Then, EEF2K renders EEF2 unable to bind ribosomes and inactive - in turn, the rate of protein synthesis is reduced.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase; calmodulin-dependent protein kinase III; EC 2.7.11.20; eEF-2 kinase; eEF-2K; EF2K; elongation factor 2 kinase; elongation factor-2 kinase; euk; eukaroytic elongation factor 2 kinase; Eukaryotic elongation factor 2 kinase; eukaryotic elongation factor-2 kinase; kinase eEF2K
基因别名: eEF-2K; EEF2K; HSU93850; SMEF2K
UniProt ID: (Human) O00418, (Rat) P70531
Entrez Gene ID: (Human) 29904, (Rat) 25435
