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Proteintech
EFTUD1 Polyclonal Antibody
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产品信息
24729-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
EFTUD1 Fusion Protein Ag20371 (772-1120 aa encoded by BC156743)
偶联物
形式
Liquid
浓度
0.38 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LIRSMEQLT SSLNEGENTH MIHQKTQEKI WEFKGKLEQH LTGRRWRNIV DQIWSFGPRK CGPNILVNKS EDFQNSVWTG PADKASKEAS RYRDLGNSIV SGFQLATLSG PMCEEPLMGV CFVLEKWDLS KFEEQGASDL AKEGQEENET CSGGNENQEL QDGCSEAFEK RTSQKGESPL TDCYGPFSGQ LIATMKEACR YALQVKPQRL MAAMYTCDIM ATGDVLGRVY AVLSKREGRV LQEEMKEGTD MFIIKAVLPV AESFGFADEI RKRTSGLASP QLVFSHWEII PSDPFWVPTT EEEYLHFGEK ADSENQARKY MNAVRKRKGL YVEEKIVEHA EKQRTLSKNK (772-1120 aa encoded by BC156743)
靶标信息
EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: elongation factor Tu GTP binding domain containing 1; Elongation factor Tu GTP-binding domain-containing protein 1; Elongation factor-like 1; Elongation factor-like GTPase 1; Protein FAM42A; ribosome assembly 1 homolog
基因别名: 4932434J20Rik; 6030468D11Rik; AI451340; AU019507; AU022896; D7Ertd791e; EFL1; EFTUD1; FAM42A; HsT19294; RIA1
UniProt ID: (Human) Q7Z2Z2, (Mouse) Q8C0D5
Entrez Gene ID: (Human) 79631, (Rat) 308789, (Mouse) 101592
