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Invitrogen
EGFL6 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-51642
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: CSFNHGICDW KQDREDDFDW NPADRDNAIG FYMAVPALAG HKKDIGRLKL LLPDLQPQSN FCLLFDYRLA GDKVGKLRVF VKNSNNALAW EKTTSEDEKW KTGKIQLYQG TDATKSIIFE AERGKGKTGE IAVDGVLLVS GLCPD
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%.
靶标信息
The EGFL6 gene encodes epidermal growth factor-like domain-containing protein 6, a member of the EGF-like repeat superfamily known for its roles in development and angiogenesis. EGFL6 is expressed at higher levels during embryonic development and has notable expression in various malignant tumors, highlighting its potential involvement in cancer progression. This secreted protein is pivotal in promoting tumor angiogenesis, influencing cancer cell migration and proliferation without affecting wound healing, making it a significant factor in tumor growth and metastasis. EGFL6 is also expressed in adipose tissues, and its role in adipose differentiation suggests it might link obesity to endometrial cancer risks. The protein impacts cellular activities such as cell adhesion, migration, and proliferation, contributing fundamentally to tumor dynamics. Consequently, EGFL6 is considered an attractive target for antibody-based therapies, with research evaluating its utility in cancer intervention strategies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EGF-like protein 6; Epidermal growth factor-like protein 6; MAM and EGF domains-containing gene protein
基因别名: EGFL6; MAEG; PP648; UNQ281/PRO320
Entrez Gene ID: (Human) 25975
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