Proteintech

EGR1 Polyclonal Antibody

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说明书
实验方案
问题与答案
技术支持
说明书
实验方案
问题与答案
技术支持
说明书
实验方案
问题与答案
技术支持
EGR1 Polyclonal Antibody

产品信息

22008-1-AP

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:1,000
查看15篇已发表文章 15篇已发表文章

免疫组化 (IHC)

-
查看6篇已发表文章 6篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:500
-

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1:50-1:500
-

免疫细胞化学 (ICC/IF)

1:50-1:500
查看5篇已发表文章 5篇已发表文章

酶联免疫吸附实验 (ELISA)

-
查看1篇已发表文章 1篇已发表文章
产品规格

种属反应

Human, Mouse

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

EGR1 Fusion Protein Ag13395 (1-363 aa encoded by BC073983)
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.27 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MAAAKAEMQ LMSPLQISDP FGSFPHSPTM DNYPKLEEMM LLSNGAPQFL GAAGAPEGSG SNSSSSSSGG GGGGGGGSNS SSSSSTFNPQ ADTGEQPYEH LTAESFPDIS LNNEKVLVET SYPSQTTRLP PITYTGRFSL EPAPNSGNTL WPEPLFSLVS GLVSMTNPPA SSSSAPSPAA SSASASQSPP LSCAVPSNDS SPIYSAAPTF PTPNTDIFPE PQSQAFPGSA GTALQYPPPA YPAAKGGFQV PMIPDYLFPQ QQGDLGLGTP DQKPFQGLES RTQQPSLTPL STIKAFATQS GSQDLKALNT SYQSQLIKPS RMRKYPNRPS KTPPHERPYA CPVESCDRRF SRSDELTRHI RIHT (1-363 aa encoded by BC073983)

靶标信息

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: AT225; Early growth response protein 1; EGR-1; Krox-24 nuclear protein; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24

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基因别名: A530045N19Rik; AT225; egr; Egr-1; EGR1; ETR103; G0S30; Krox-1; KROX-24; KROX24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; ZIF-268; Zif268; ZNF225

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UniProt ID: (Human) P18146, (Mouse) P08046

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Entrez Gene ID: (Human) 1958, (Mouse) 13653

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功能
transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding histone acetyltransferase binding sequence-specific DNA binding metal ion binding RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding nucleic acid binding double-stranded DNA binding transcription factor binding transcription regulatory region DNA binding C2H2 zinc finger transcription factor
参与通路
negative regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter response to glucose T cell differentiation BMP signaling pathway response to insulin regulation of protein sumoylation skeletal muscle cell differentiation regulation of apoptotic process positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter type I interferon signaling pathway regulation of transcription from RNA polymerase II promoter in response to hypoxia interleukin-1-mediated signaling pathway cellular response to gamma radiation cellular response to heparin cellular response to mycophenolic acid glomerular mesangial cell proliferation positive regulation of glomerular metanephric mesangial cell proliferation negative regulation of canonical Wnt signaling pathway transcription, DNA-templated regulation of transcription, DNA-templated learning or memory positive regulation of gene expression positive regulation of cell death negative regulation of apoptotic process positive regulation of neuron apoptotic process regulation of long-term neuronal synaptic plasticity cellular response to organic substance cellular response to cAMP cellular response to gonadotropin stimulus
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