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Proteintech
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Immunogen sequence: LEISDEFSE AIGALRGHED KIRVVLNKAD MVETQQLMRV YGALMWALGK VVGTPEVLRV YIGSFWSQPL LVPDNRRLFE LEEQDLFRDI QGLPRHAALR KLNDLVKRAR LVRVHAYIIS YLKKEMPSVF GKENKKKQLI LKLPVIFAKI QLEHHISPGD FPDCQKMQEL LMAHDFTKFH SLKPKLLEAL DEMLTHDIAK LMPLLRQEEL ESTEVGVQGG AFEGTHMGPF VERGPDEAME DGEEGSDDEA EWVVTKDKSK YDEIFYNLAP ADGKLSGSKA KTWMVGTKLP NSVLGRIWKL SDVDRDGMLD DEEFALASHL IEAKLEGHGL PANLPRRLVP PSKRRHKGSA E (194-543 aa encoded by BC014445)
This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EH domain-containing protein 2; EH-domain containing 2; FLJ96617; PAST homolog 2; putative eps protein
基因别名: BC027084; C130052H20Rik; EHD2; MGEPS; PAST2
UniProt ID: (Human) Q9NZN4, (Rat) Q4V8H8, (Mouse) Q8BH64
Entrez Gene ID: (Human) 30846, (Rat) 361512, (Mouse) 259300