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Invitrogen
EHHADH Polyclonal Antibody
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产品信息
PA5-89260
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 444-723 of human EHHADH (NP_0019572)
偶联物
形式
Liquid
浓度
0.94 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: EVIPSQYSSP TTIATVMNLS KKIKKIGVVV GNCFGFVGNR MLNPYYNQAY FLLEEGSKPE EVDQVLEEFG FKMGPFRVSD LAGLDVGWKS RKGQGLTGPT LLPGTPARKR GNRRYCPIPD VLCELGRFGQ KTGKGWYQYD KPLGRIHKPD PWLSKFLSRY RKTHHIEPRT ISQDEILERC LYSLINEAFR ILGEGIAASP EHIDVVYLHG YGWPRHKGGP MFYASTVGLP TVLEKLQKYY RQNPDIPQLE PSDYLKKLAS QGNPPLKEWQ SLAGSPSSKL; Positive Samples: HepG2, Mouse liver, Rat liver, Rat kidney; Cellular Location: Peroxisome
靶标信息
As an L-hydroxy-specific enzyme, EHHADH (enoyl-CoA-hydratase:3-hydroxyacyl-CoA dehydrogenase), also known as Peroxisomal L-bifunctional enzyme, is a 723 amino acid protein has an essential tripeptide sequence on its carboxyl-terminus that is required for peroxisomal transport. EHHADH-null mice only exhibit a blunted peroxisome proliferative response when challenged with a peroxisome proliferator. Since there were no observed changes in lipid metabolism, this evidence suggests that enoyl-CoAs were diverted to the D-hydroxy-specific beta-oxidation system for metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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