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Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18. Involved in the regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950). Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing (PubMed:23664528). May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation (PubMed:14521927). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Band 4.1-like protein 4B; Erythrocyte membrane protein band 4.1-like 4B; erythrocyte protein band 4.1-like 4b; erythrocyte protein band 4.1-like 4b; expressed in high-metastatic cells; expressed in high-metastatic cells; FERM-containing protein CG1; Protein EHM2
基因别名: 6430543G08Rik; AA589614; AU021054; BB007528; CG1; D4Ertd346e; EHM2; Epb4.1l4b; EPB41L4B; LULU2; RGD1562988
UniProt ID: (Human) Q9H329, (Mouse) Q9JMC8, (Rat) B2RYE5
Entrez Gene ID: (Human) 54566, (Mouse) 54357, (Rat) 500464