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Immunogen sequence: PDKLSDCDDS IALSFWKAIE KEATSWMVKA ETFHFVFGSF KLERSAPKPR LEHQKKVRKM EENGNMPTKL QKLDLSSYPE A
Highest antigen sequence identity to the following orthologs: Mouse - 60%, Rat - 32%.
Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. [UniProt]
Protein Aliases: E1A-like inhibitor of differentiation 3; EID-1-like inhibitor of differentiation 3; EID-3; EID3; EP300-interacting inhibitor of differentiation 3; non-SMC element 4 homolog B; Non-structural maintenance of chromosomes element 4 homolog B; NS4EB; testis tissue sperm-binding protein Li 96mP
Gene Aliases: EID3; NS4EB; NSE4B; NSMCE4B
UniProt ID: (Human) Q8N140
Entrez Gene ID: (Human) 493861