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Proteintech
EIF3C Polyclonal Antibody
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产品信息
12733-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
EIF3C Fusion Protein Ag3438 (1-324 aa encoded by BC001571)
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSRFFTTGS DSESESSLSG EELVTKPVGG NYGKQPLLLS EDEEDTKRVV RSAKDKRFEE LTNLIRTIRN AMKIRDVTKC LEEFELLGKA YGKAKSIVDK EGVPRFYIRI LADLEDYLNE LWEDKEGKKK MNKNNAKALS TLRQKIRKYN RDFESHITSY KQNPEQSADE DAEKNEEDSE GSSDEDEDED GVSAATFLKK KSEAPSGESR KFLKKMDDED EDSEDSEDDE DWDTGSTSSD SDSEEEEGKQ TALASRFLKK APTTDEDKKA AEKKREDKAK KKHDRKSKRL DEEEEDNEGG EWERVRGGVP LVKEKPKMFA KGTEI (1-324 aa encoded by BC001571)
靶标信息
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell migration-inducing protein 17; eIF3 p110; eIF3 p110 {ECO:0000255|HAMAP-Rule:MF_03002}; eIF3c; eIF3c {ECO:0000255|HAMAP-Rule:MF_03002}; Eukaryotic translation initiation factor 3 subunit 8; eukaryotic translation initiation factor 3 subunit 8 {ECO:0000255|HAMAP-Rule:MF_03002}; Eukaryotic translation initiation factor 3 subunit C; eukaryotic translation initiation factor 3 subunit C {ECO:0000255|HAMAP-Rule:MF_03002}; eukaryotic translation initiation factor 3, subunit 8 (110 kDa); eukaryotic translation initiation factor 3, subunit 8 (110kD); eukaryotic translation initiation factor 3, subunit 8, 110kDa; eukaryotic translation initiation factor 3, subunit C; extra-toes spotting; NIPI-like protein
基因别名: 110kDa; 3230401O13Rik; eIF3-p110; EIF3C; EIF3CL; EIF3S8; NIPIL(A3); NipilA3; Xs; Xsl
UniProt ID: (Human) Q99613, (Mouse) Q8R1B4, (Rat) B5DFC8
Entrez Gene ID: (Human) 8663, (Mouse) 56347, (Rat) 293484
