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Proteintech
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Immunogen sequence: SYERRNEGAA RVIGTLLGTV DKHSVEVTNC FSVPHNESED EVAVDMEFAK NMYELHKKVS PNELILGWYA TGHDITEHSV LIHEYYSREA PNPIHLTVDT SLQNGRMSIK AYVSTLMGVP GRTMGVMFTP LTVKYAYYDT ERIGVDLIMK TCFSPNRVIG LSSDLQQVGG ASARIQDALS TVLQYAEDVL SGKVSADNTV GRFLMSLVNQ VPKIVPDDFE TMLNSNINDL LMVTYLANLT QSQIALNEKL VNL
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Deubiquitinating enzyme eIF3f; eIF-3-epsilon; eIF3 p47; eIF3-epsilon; EIF3F; Eukaryotic translation initiation factor 3 subunit 5; eukaryotic translation initiation factor 3 subunit 5 epsilon; Eukaryotic translation initiation factor 3 subunit F; eukaryotic translation initiation factor 3, subunit 5 (epsilon); eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD); eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa; eukaryotic translation initiation factor 3, subunit F
基因别名: 0610037M02Rik; AA409853; eIF3-p47; EIF3F; EIF3S5
UniProt ID: (Human) O00303, (Mouse) Q9DCH4
Entrez Gene ID: (Human) 8665, (Mouse) 66085, (Rat) 293427