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Proteintech
EIF3I Polyclonal Antibody
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产品信息
11287-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Hamster,
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
EIF3I Fusion Protein Ag1847 (1-325 aa encoded by BC000413)
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MKPILLQGH ERSITQIKYN REGDLLFTVA KDPIVNVWYS VNGERLGTYM GHTGAVWCVD ADWDTKHVLT GSADNSCRLW DCETGKQLAL LKTNSAVRTC GFDFGGNIIM FSTDKQMGYQ CFVSFFDLRD PSQIDNNEPY MKIPCNDSKI TSAVWGPLGE CIIAGHESGE LNQYSAKSGE VLVNVKEHSR QINDIQLSRD MTMFVTASKD NTAKLFDSTT LEHQKTFRTE RPVNSAALSP NYDHVVLGGG QEAMDVTTTS TRIGKFEARF FHLAFEEEFG RVKGHFGPIN SVAFHPDGKS YSSGGEDGYV RIHYFDPQYF EFEFEA (1-325 aa encoded by B C000413)
靶标信息
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: eIF-3-beta; eIF3 p36; eIF3i; Eukaryotic translation initiation factor 3 subunit 2; Eukaryotic translation initiation factor 3 subunit I; eukaryotic translation initiation factor 3, subunit 1; eukaryotic translation initiation factor 3, subunit 2 (beta); eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa; eukaryotic translation initiation factor 3, subunit I; predicted protein of HQ2242; subuni; TGF-beta receptor binding protein; TGF-beta receptor-interacting protein 1; TGFbeta receptor-interacting protein 1; TRIP-1
基因别名: 36kDa; D4Ertd632e; eIF3-beta; eIF3-p36; EIF3I; EIF3S2; PRO2242; TRIP-1; TRIP1
UniProt ID: (Human) Q13347, (Mouse) Q9QZD9, (Rat) B0BNA7
Entrez Gene ID: (Human) 8668, (Mouse) 54709, (Rat) 682390
