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Proteintech
EIF4H Polyclonal Antibody
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产品信息
11012-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
EIF4H Fusion Protein Ag1468 (1-188 aa encoded by BC010021)
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
EIF4H has two isoforms. The short isoform (~25kDa) is the predominant isoform and is expressed alone in liver and skeletal muscle. This is a rabbit anti-EIF4H polyclonal antibody raised against part of N-terminal chain of human EIF4H, and can recognize both isoforms.
Immunogen sequence: MADFDTYDD RAYSSFGGGR GSRGSAGGHG SRSQKELPTE PPYTAYVGNL PFNTVQGDID AIFKDLSIRS VRLVRDKDTD KFKGFCYVEF DEVDSLKEAL TYDGALLGDR SLRVDIAEGR KQDKGGFGFR KGGPDDRGFR DDFLGGRGGS RPGDRRTGPP MGSRFRDGPP LRGSNMDFRE PTEEERAQR (1-188 aa encoded by BC010021 )
靶标信息
This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: eIF-4H; Eukaryotic translation initiation factor 4H; Williams-Beuren syndrome chromosomal region 1 protein; Williams-Beuren syndrome chromosome region 1
基因别名: eIF-4H; EIF4H; KIAA0038; WBSCR1; WSCR1
UniProt ID: (Human) Q15056
Entrez Gene ID: (Human) 7458
nucleotide binding
RNA binding
translation initiation factor activity
helicase activity
protein binding
translation factor activity, RNA binding
RNA strand annealing activity
RNA strand-exchange activity
ribosomal small subunit binding
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion
translation initiation factor
