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Invitrogen
EKLF Polyclonal Antibody
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EKLF Antibody (PA5-86441) in WB
Western blot analysis of EKLF in Lane 1: C6 whole cell lysate (40 µg), Lane 2: SP2/0 whole cell lysate (40 µg), Lane 3: MCF-7 whole cell lysate (40 µg), Lane 4: K562 whole cell lysate (40 µg). Sample was incubated with EKLF polyclonal antibody (Product # PA5-86441) using a 1:500 dilution.
产品信息
PA5-86441
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide, corresponding to amino acids 288-335 of Human EKLF.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Purity is > 95% by SDS-PAGE.
靶标信息
KLF1 is a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant Inblood phenotype.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EKLF; Erythroid krueppel-like transcription factor; erythroid Kruppel-like factor; erythroid transcription factor; erythroid-specific transcription factor EKLF; Krueppel-like factor 1; Kruppel-like factor 1 (erythroid); monoclonal antibody A3D8; neonatal anemia; truncated EKLF; truncated erythroid Kruppel-like factor 1
基因别名: CDAN4; EKLF; HBFQTL6; INLU; KLF1; Nan
UniProt ID: (Human) Q13351
Entrez Gene ID: (Human) 10661, (Rat) 304666, (Mouse) 16596
core promoter proximal region sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
protein domain specific binding
activating transcription factor binding
nucleic acid binding
DNA binding
C2H2 zinc finger transcription factor
transcription, DNA-templated
regulation of transcription, DNA-templated
erythrocyte differentiation
positive regulation of transcription, DNA-templated
cellular response to peptide
in utero embryonic development
liver development
chromatin remodeling
embryonic hemopoiesis
erythrocyte maturation
positive regulation of transcription from RNA polymerase II promoter
erythrocyte development
