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Proteintech
ELAC2 Recombinant Rabbit Monoclonal Antibody (240487B6)
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产品信息
83468-6-RR
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
240487B6
抗原
ELAC2 fusion protein Ag0105
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: NCGEGVQRLM QEHKLKVARL DNIFLTRMHW SNVGGLSGMI LTLKETGLPK CVLSGPPQLE KYLEAIKIFS GPLKGIELAV RPHSAPEYED ETMTVYQIPI HSEQRRGKHQ PWQSPERPLS RLSPERSSDS ELNENEPHLP HGVSQRRGVR DSSLVVAFIC KLHLKRGNFL VLKAKEMGLP VGTAAIAPII AAVKDGKSIT HEGREILAEE LCTPPDPGAA FVVVECPDES FIQPICENAT FQRYQGKADA PVALVVHMAP ASVLVDSRYQ QWMERFGPDT QHLVLNENCA SVHNLRSHKI
靶标信息
ELAC2 encodes a protein that has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: elaC homolog 2; ElaC homolog protein 2; elaC-like protein 2; Heredity prostate cancer protein 2; putative prostate cancer susceptibility protein HPC2/ELAC2; Ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z (long form); tRNase Z 2; Zinc phosphodiesterase ELAC protein 2
基因别名: COXPD17; ELAC2; ELC2; HPC2
UniProt ID: (Human) Q9BQ52
Entrez Gene ID: (Human) 60528
