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Proteintech
ELP2 Polyclonal Antibody
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产品信息
13793-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ELP2 fusion protein Ag4581
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: AITGQSLNHV LCNQDSDLPE GATVPALGLS NKAVFQGDIA SQPSDEEELL TSTGFEYQQV AFQPSILTEP PTEDHLLQNT LWPEVQKLYG HGYEIFCVTC NSSKTLLASA CKAAKKEHAA IILWNTTSWK QVQNLVFHSL TVTQMAFSPN EKFLLAVSRD RTWSLWKKQD TISPEFEPVF SLFAFTNKIT SVHSRIIWSC DWSPDSKYFF TGSRDKKVVV WGECDSTDDC IEHNIGPCSS VLDVGGAVTA VSVCPVLHPS QRYVVAVGLE CGKICLYTWK KTDQVPEIND WTHCVETSQS QSHTLAIRKL CWKNCSGKTE QKEAEGAEWL HFASCGEDHT VKIHRVNKCA L
靶标信息
ELP2 regulates the ligand-dependent activation of STAT3. The protein acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: elongation protein 2 homolog; Elongator complex protein 2; elongator protein 2; ELP2; SHINC-2; signal transducer and activator of transcription 3 interacting protein 1; signal transducer and activator of transcription interacting protein 1; STAT3-interacting protein 1; StIP1
基因别名: AU023723; ELP2; Epl2; SHINC-2; STATIP1; StIP; StIP1
UniProt ID: (Human) Q6IA86, (Mouse) Q91WG4, (Rat) Q496Z0
Entrez Gene ID: (Human) 55250, (Mouse) 58523, (Rat) 307545
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of JAK-STAT cascade
transcription elongation from RNA polymerase II promoter
positive regulation of endopeptidase activity
proteasome assembly
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
