Invitrogen

ELP3 Recombinant Rabbit Monoclonal Antibody (8H8L24)

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ELP3 Antibody (702669) in WB

Western blot analysis was performed on whole cell extracts (30 µg lysate) of IMR-32 (Lane 1), U-87 MG (Lane 2), HeLa (Lane 3), A549 (Lane 4), Neuro-2a (Lane 5), HT-29 (Lane 6), MDA-MB-231 (Lane 7) and tissue extract (30 µg lysate) of Mouse Brain (Lane 8). The blot was probed with Anti-ELP3 Recombinant Rabbit Monoclonal Antibody (Product # 702669, 1:200 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 1:4000 dilution). A ~62 kDa band corres... View More

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ELP3 Antibody — Antibody specificity was demonstrated by siRNA mediated knockdown of target protein. SH-SY5Y cells were transfected with ELP3 siRNA and decrease in signal intensity was observed in Western blot application using Anti-ELP3 Recombinant Rabbit Monoclonal Antibody (Product # 702669). {KD}

产品信息

702669

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

Expression System

Expi293

分类

Recombinant Monoclonal

类型

Antibody

克隆号

8H8L24

抗原

Peptides corresponding to human ELP3 [1) aa120-aa139, 2) aa28-aa45]

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2724251

产品详细信息

This antibody is predicted to react with Monkey, Pig, Horse, Bovine.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

Elongator complex protein 3 (ELP3) is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. It may also have a methyltransferase activity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。