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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: QMISSLKTQI QSQESDLKSQ EDDLNRAKSE LNRLQQEETQ LEQSIQAGRV QLETIIKSLK STQDEINQAR SKLSQLHESR QEAHRSLEQY DQVLDGAHGA SLTDLANLSE GVSLAERGSF GAMDDPFKNK ALLFSNNTQE LHPDPFQTED PFKSDPFKGA DPFKGDPFQN DPFAEQQTTS TDPFGGDPFK ESDPFRGSAT DDFFKKQTKN DPFTSDPFTK NPSLPSKLDP FESSDPFSSS SVSSKGSDPF GTLDPFGSGS FNSAEGFADF SQMSKVKVHL
Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Epidermal growth factor receptor substrate 15-like 1; Eps15-related protein; Eps15R
基因别名: EPS15L1; EPS15R
Entrez Gene ID: (Human) 58513