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Invitrogen
ERCC6L Polyclonal Antibody
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产品信息
PA5-62199
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human ERCC6L
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: IIWIRLVPLQ EEIYRKFVSL DHIKELLMET RSPLAELGVL KKLCDHPRLL SARACCLLNL GTFSAQDGNE GEDSPDVDHI DQVTDDTLME ESGKMIFLMD LL
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 81%.
靶标信息
ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint. ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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