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Invitrogen
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PA1-21016 detects ERK2 in Human, Mouse and Rat samples.
PA1-21016 has been successfully used in Immunohistochemistry (Paraffin), ChIP, Immunoprecipitation and Western Blot procedures.
PA1-21016 immunogen corresponds to Synthetic peptide corresponding to the C-terminal region of the mouse protein.
MAPK1 (ERK2) is a serine/threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.
仅用于科研。不用于诊断过程。未经明确授权不得转售。