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Invitrogen
ESAM Polyclonal Antibody
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ESAM Antibody (PA5-48019) in IHC (P)
Immunohistochemical analysis of ESAM in immersion fixed paraffin-embedded sections of mouse kidney. Samples were incubated with ESAM Polyclonal Antibody (Product # PA5-48019) using a dilution of 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG HRP Secondary Antibody. Tissue was stained with DAB (brown) and counterstained with hematoxylin (blue).
产品信息
PA5-48019
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse ESAM Gln30-Ser248 (predicted)
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs and Western blots, approximately 15% cross-reactivity with recombinant human ESAM is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
靶标信息
ESAM is a 55-kDa membrane protein composed of 2 extracellular Ig domains, a single transmembrane domain, and a 120 amino acid cytoplasmic domain. ESAM is related to members of the junctional adhesion molecule (JAM) family, and is expressed on endothelial cells and activated platelets. ESAM at endothelial tight junctions plays a role in the regulation of vascular permeability, in response to agents such as VEGF or extravasating neutrophils.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Endothelial cell-selective adhesion molecule
基因别名: 2310008D05Rik; Esam; Esam1; W117m
UniProt ID: (Mouse) Q925F2
Entrez Gene ID: (Mouse) 69524
