应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
0.25-2 µg/mL | - |
产品规格 | |
---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide (143 FFREEKEQRGTFNFKVPE 160) of Embigin protein. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.5 mg/mL |
纯化类型 |
Protein A |
保存液 |
PBS with 0.05% BSA |
内含物 |
0.05% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2540781 |
Embigin is a 327 amino acid regulatory protein belonging to the immunoglobulin superfamily class of CAMs, and has two Ig-like (immunoglobulin-like) V- type domains. In situ hybridization analysis shows that Embigin has specific carbohydrate epitopes and plays an important role in early postimplantation embryogenesis. A highly glycosylated transmembrane glycoprotein, Embigin acts as a regulator of cell/ECM interactions during development and homeostasis of normal adult tissues. Transfection studies suggest its role in promotion of integrin-mediated cell-substratum adhesion. Widely expressed in most of the tissues and embryonal carcinoma cells, prostate and mammary cancer cell lines, it may also help in the classification of human carcinomas.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Embigin; embigin homolog; glycoprotein 70; Teratocarcinoma glycoprotein Gp-70
基因别名: AL022799; EMB; GP70
UniProt ID: (Human) Q6PCB8, (Mouse) P21995
Entrez Gene ID: (Human) 133418, (Mouse) 13723
分子生物学功能:
scaffold/adaptor protein