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PA3-067 detects Endothelin 1 from human, mouse, and rat samples.
PA3-067 has been successfully used in Western blot, immunocytochemistry, and immunohistochemistry procedures. By Western blot, this antibody detects a 24.4 kDa protein corresponding to mouse Endothelin 1.
The PA3-067 antigen is mouse Endothelin-1 CS-Abu-SSLMDKE-Abu-VYF-Abu-HLDIIW coupled to KLH.
The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Big endothelin 1; Big ET; Big ET 1; Big ET1; BigET; Endothelin-1; Et; ET-1; PPET1; preproendothelin; Preproendothelin-1
基因别名: ARCND3; EDN1; ET-1; ET1; HDLCQ7; PPET1; preproET; QME
UniProt ID: (Human) P05305, (Rat) P22388, (Mouse) P22387
Entrez Gene ID: (Human) 1906, (Rat) 24323, (Mouse) 13614