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Invitrogen
Enterotoxin D Recombinant Mouse Monoclonal Antibody (4G12)
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Enterotoxin D Antibody (MA566522) in SDS-PAGE
SDS-PAGE characterization of Enterotoxin D under reducing conditions. Lane M: Protein marker (kDa); Lane ETD-C: Purified Enterotoxin D Recombinant Monoclonal (Product # MA566522). Enterotoxin D showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-314.
产品信息
MA566522
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4G12
抗原
Enterotoxin D.
偶联物
形式
Liquid
浓度
14.1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Enterotoxin D is one of several exotoxins produced by the bacterium Staphylococcus aureus, which is commonly associated with staphylococcal food poisoning. As a member of the staphylococcal enterotoxin family, Enterotoxin D is a heat-stable protein that can withstand cooking processes, posing a significant risk in food safety when foods are contaminated. It functions as a superantigen, meaning it can indiscriminately activate a large number of T-cells by bridging the major histocompatibility complex (MHC) class II molecules on antigen-presenting cells with T-cell receptors. This results in a massive immune response characterized by the release of pro-inflammatory cytokines, leading to symptoms such as vomiting, diarrhea, and abdominal cramps, which typically occur within hours of ingestion. Enterotoxin D, like other staphylococcal enterotoxins, is recognized for its role in triggering these rapid and intense immune responses. Its stability and biological activity necessitate stringent control measures in food production and processing environments to prevent outbreaks of foodborne illness.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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