Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Enterovirus 71 3D Monoclonal Antibody (4)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 2
Enterovirus 71 3D Antibody (MA5-35903) in WB
Western Blot analysis of Enterovirus 71 3D in A) 30 µg RD whole cell lysate/extract; B) 30 µg whole cell lysate/extract of Enterovirus 71 (EV71) infected RD cells. Sample was separated with 7.5% SDS-PAGE, incubated with monoclonal antibody (Product # MA5-35903) at a dilution of 1:5,000.
产品信息
MA5-35903
应用
建议稀释比
已发表文章
产品规格
种属反应
Virus
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
4
抗原
The immunogen used to generate this antibody corresponds to EV71 3D.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7, with 20% glycerol
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
EV71 is a positive-sense single-stranded RNA virus of the Picornaviridae family. It is known to cause hand, foot, and mouth disease and various neurological pathological conditions, such as aseptic meningitis and ataxia. EV71 is shown to utilize host UDP-glucose glycoprotein glucosyltransferase 1 (UGGT1) to enhance viral replication and virulence. It forms replication complexes (RCs) on cellular membranes that contain a mix of host and viral proteins to facilitate viral replication. During infection viral RNA replication occurs on the cytoplasmic surfaces of single-membrane vesicles derived from the endoplasmic reticulum, and the membranes can serve to accelerate RC assembly during positive-strand genomic RNA replication. It has been shown that 3D polymerase, an RNA-dependent RNA polymerase that is encoded in the P3 viral genome region, plays a key role in EVA71 replication. Neural progenitor cells are shown to be prone to EV71 infection and that these stem cells can support the active replication of this virus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
