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Invitrogen
EphB2 Polyclonal Antibody
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EphB2 Antibody (PA1-30297) in ICC/IF
Immunofluorescent analysis of EphB2 in A375 cells using an EphB2 polyclonal antibody (Product # PA1-30297) followed by detection using an Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red) and DAPI was used to stain the nuclei (blue).
产品信息
PA1-30297
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide conjugated to KLH, corresponding to amino acids 1036-1051 of Human Eph B2.
偶联物
形式
Liquid
浓度
0.25 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA1-30297 detects EphB2 from human samples.
PA1-30297 has been successfully used in immunohistochemistry (paraffin tissue), Western blot, and ELISA applications. Suggested positive controls for this produt is NCI-H460 cell lysate and breast carcinoma.
The PA1-30297 immunogen is a synthetic peptide conjugated to KLH, corresponding to amino acids 1036-1051 of Human Eph B2.
Store at 4°C short term. For extended storage aliquot and store at -20°C, avoiding freeze/thaw cycles.
靶标信息
EPHB2 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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