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Invitrogen
Ephrin B1 Polyclonal Antibody
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产品信息
PA1-30383
产品规格
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment (extracellular domain) (Rat). Expressed in NSO cells
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
PA1-30383 detects EphB1 from rat samples.
PA1-30383 has been successfully used in ELISA, Western blot applications.
The PA1-30383 immunogen is: Recombinant fragment (extracellular domain) (Rat). Expressed in NSO cells
靶标信息
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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