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Invitrogen
ErbB2 Monoclonal Antibody (2G11), FITC
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ErbB2 Antibody (AHO0918)
ErbB-2 (also known as Her-2 or neu) is a 185 kDa transmembrane receptor tyrosine kinase from the EGFR family that acts to regulate a variety of biological responses including cell growth, differentiation, and tissue development. ErbB-2 forms complexes with other members of the EGFR receptor family. Binding of growth factors to these related receptors leads to phosphorylation on several tyrosine residues within the cytoplasmic domain of ErbB-2, thus activating the receptor. A direct link between overexpression of ErbB-2 in breast and ovaria... View More
产品信息
AHO0918
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2G11
抗原
Recombinant human p185/HER-2.
偶联物
FITC
FITC
FITC
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
保存条件
4°C, store in dark
运输条件
Wet ice (domestic); Wet or Dry ice (international)
RRID
靶标信息
ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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