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Invitrogen
Etomidate Recombinant Mouse Monoclonal Antibody (2C3)
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Etomidate Antibody (MA566514) in SDS-PAGE
SDS-PAGE characterization of Etomidate under reducing conditions. Lane M: Protein marker (kDa); Lane ETM: Purified Etomidate Recombinant Monoclonal (Product # MA566514). Etomidate showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-344.
产品信息
MA566514
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2C3
抗原
Conjugate of ETM hapten and KLH.
偶联物
形式
Liquid
浓度
6 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Etomidate is a hypnotic agent primarily used for the induction of anesthesia, functioning as a positive allosteric modulator on the gamma-aminobutyric acid type A receptor, thereby enhancing the inhibitory effects of gamma-aminobutyric acid. This intravenous hypnotic is utilized for anesthesia induction, maintenance, critical care sedation, and treating Cushing's disease. Despite its benefits, etomidate is associated with undesirable effects such as pain on injection, myoclonus, CNS excitation, adrenocortical depression, and postoperative nausea and vomiting. The pharmaceutical design of etomidate aims to address these issues, with ongoing research exploring alternative administration routes and dosage forms to expand its application. While etomidate remains clinically relevant due to its hemodynamic stability and rapid onset and offset, alternatives like propofol, ketamine, and remimazolam are being considered due to fewer side effects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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