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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: AQLSDPGVCV SSDTLDGNSS SAGSSCNSPA KVSTTTDSPV SPAQAASPFI PLDE
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 96%.
Acts as an inhibitor of serine/threonine-protein phosphatase 2A (PP2A) activity. Potentiates ubiquitin-mediated proteasomal degradation of serine/threonine-protein phosphatase 2A catalytic subunit alpha (PPP2CA). Inhibits PP2A-mediated dephosphorylation of WEE1, promoting ubiquitin- mediated proteolysis of WEE1, thereby releasing G2/M checkpoint.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: family with sequence similarity 122A; PABIR family member 1; protein FAM122A; unnamed protein product
基因别名: C9orf42; FAM122A
UniProt ID: (Human) Q96E09
Entrez Gene ID: (Human) 116224