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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PSSHGLAKTA ATVFSKSFEQ VSGVTVPHNP SSAVGCGAGT DANRFSACSL QEEKLIYVSE RTELPMKHQS GQQ
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 77%.
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: down regulated by Ctnnb1, a; down-regulated by CTNNB1 protein A; family with sequence similarity 126 member A; unnamed protein product
基因别名: DRCTNNB1A; FAM126A; HCC; HLD5
UniProt ID: (Human) Q9BYI3
Entrez Gene ID: (Human) 84668