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Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: down regulated by Ctnnb1, a; Down-regulated by CTNNB1 protein A; down-regulated by Ctnnb1, A; family with sequence similarity 126, member A; Hyccin
基因别名: AB030242; DRCTNNB1A; FAM126A; HCC; HLD5; HYCC1; RGD1562906
UniProt ID: (Human) Q9BYI3, (Mouse) Q6P9N1
Entrez Gene ID: (Human) 84668, (Mouse) 84652, (Rat) 499975