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Invitrogen
FAM213A Polyclonal Antibody
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FAM213A Antibody (PA5-48580) in IHC (P)
Immunohistochemical analysis of C10orf58 in formalin fixed and paraffin embedded human skin tissue. Samples were probed with a C10orf58 Antibody (C-term) (Product # PA5-48580) followed by peroxidase conjugation of the secondary antibody and DAB staining.
产品信息
PA5-48580
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 181-209 amino acids from the C-terminal region of human C10orf58.
偶联物
形式
Liquid
浓度
Lot-Specific
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
Predicted to react with bovine based on sequence homology.
靶标信息
Involved in redox regulation of the cell (PubMed:26438880, PubMed:19951071). Acts as an antioxidant (PubMed:19951071, PubMed:26438880). Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (PubMed:19951071). May affect bone resorption and help to maintain bone mass (PubMed:19951071). Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway (PubMed:26438880). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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