Proteintech

FAM35A Polyclonal Antibody

Name: FAM35A Polyclonal Antibody
Brand: Proteintech
SKU: 26090-1-AP

查看其他3个FAM35A抗体

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

图: 1 / 1

FAM35A Antibody (26090-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with 26090-1-AP (FAM35A antibody) at dilution of 1:1,000 incubated at room temperature for 1.5 hours.

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Immunogen image

Immunogen Image FAM35A Polyclonal Antibody

产品信息

26090-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

酶联免疫吸附实验 (ELISA)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

FAM35A fusion protein Ag23416

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.6 mg/mL

90 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

产品详细信息

Immunogen sequence: MSGGSQVHIF WGAPIAPLKI TVSEDTASLM SVADPWKKIQ LLYSQHSLYL KDEKQHKNLE NYKVPESIGS PDLSGHFLAN CMNRHVHVKD DFVRSVSETQ NIESQKIHSS RLSDITSSNM QICGFKSTVP HFTEEEKYQK LLSENKIRDE QPKHQPDICG KNFNTNLFQL GHKCAAVLDL VCSTEKINIG PEVVQRECVP TEYHEIQNQC LGLFSSNAVD KSRSEAAVRK VSDLKISTDT EFLSIITSSQ VAFLAQKKDK RRSPVNKGNV NMETEPKASY GEIRIPEENS IQLDGFTEAY ESGQNQAYSL ELFSPVCPKT ENSRIHINSD KGLEEHTGSQ ELFSSEDELP

靶标信息

Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs) (PubMed:29656893, PubMed:29789392). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (PubMed:29656893, PubMed:29789392). Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres (PubMed:29656893). [UniProt]

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: family with sequence similarity 35 member A; Protein FAM35A; RINN1-REV7-interacting novel NHEJ regulator 2; Shield complex subunit 2; Shieldin complex subunit 2; unnamed protein product

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基因别名: bA163M19.1; FAM35A; FAM35A1; RINN2; SHLD2

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UniProt ID: (Human) Q86V20

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Entrez Gene ID: (Human) 54537

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功能

protein binding

参与通路

somatic diversification of immunoglobulins involved in immune response DNA repair cellular response to DNA damage stimulus regulation of double-strand break repair via homologous recombination telomere maintenance in response to DNA damage positive regulation of isotype switching negative regulation of double-strand break repair via homologous recombination positive regulation of double-strand break repair via nonhomologous end joining