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产品信息
PA5-50661
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:50-1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide corresponding to a region derived from internal residues of human FAT atypical cadherin 1 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
2.4 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2636113 |
产品详细信息
The antibody detects endogenous levels of total FAT1 protein.
靶标信息
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cadherin family member 7; cadherin ME5; cadherin-related family member 8; Cadherin-related tumor suppressor homolog; FAT tumor suppressor 1; Protein fat homolog; Protocadherin Fat 1; Protocadherin Fat 1, nuclear form
基因别名: CDHF7; CDHR8; FAT; FAT1; hFat1; ME5
UniProt ID: (Human) Q14517
Entrez Gene ID: (Human) 2195
分子生物学功能:
cadherin
