Search Thermo Fisher Scientific
The antibody detects endogenous levels of total FAT3 protein.
FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). The atypical cadherin Fat3 ensures that retinal amacrine cells (ACs) develop this unipolar morphology. Fat3 expression was restricted to the nervous system, for example in the brain, it is expressed in a variety of regions and axon fascicles. However, its strongest expression was observed in the olfactory bulb and retina.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cadherin family member 15; cadherin-related family member 10; FAT tumor suppressor homolog 3; hFat3; Protocadherin Fat 3
基因别名: CDHF15; CDHR10; FAT3; hFat3; KIAA1989
UniProt ID: (Human) Q8TDW7
Entrez Gene ID: (Human) 120114
分子生物学功能: cadherin