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Antibody detects endogenous levels of total FBXO17.
F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: F Box Gama 4; F-box only protein 17; F-box only protein 26; F-box protein FBG4; FLJ11798; FLJ25205; FLJ58300; MGC9379
基因别名: FBG4; FBX17; FBX26; FBXO17; FBXO26
UniProt ID: (Human) Q96EF6, (Rat) Q6AY27, (Mouse) Q9QZM8
Entrez Gene ID: (Human) 115290, (Rat) 292757, (Mouse) 50760