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Bethyl Laboratories
FBP11 Polyclonal Antibody
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FBP11 Antibody (A304-736A) in WB
Detection of human FBP11 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-FBP11 antibody (Product # A304-736A) (lot A304-736A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 10 seconds.
产品信息
A304-736A
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 275 to 325 of human Formin-Binding Protein 11.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
FNBP3, Formin-binding protein 3, is a 957 amino acid protein encoded by the human gene PRPF40A. FNBP3 belongs to the PRPF40 family and contains five FF domains and two WW domains. Nuclear proteins harboring both WW and FF protein interaction modules bind to splicing factors as well as RNA polymerase II and may serve to link transcription with splicing. Through the WW domains, FNBP3 will bind to the Formin proline-rich regions. Also known as Pre-mRNA-processing factor 40 homolog A, FNBP3 binds to WASL/N-WASP (Neuronal Wiskott-Aldrich syndrome protein) complex and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. FNBP3 is widely expressed in most tissues and is localized to the nuclear speckles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fas ligand-associated factor 1; Fas-ligand associated factor 1; FLJ20585; formin binding protein 3; Formin-binding protein 11; Formin-binding protein 3; HIP-10; Huntingtin yeast partner A; Huntingtin-interacting protein 10; Huntingtin-interacting protein A; NY-REN-6 antigen; Pre-mRNA-processing factor 40 homolog A; PRP40 pre-mRNA processing factor 40 homolog A; Renal carcinoma antigen NY-REN-6
基因别名: FBP-11; FBP11; FLAF1; FNBP3; HIP-10; HIP10; HSPC225; HYPA; NY-REN-6; Prp40; PRPF40A
UniProt ID: (Human) O75400
Entrez Gene ID: (Human) 55660
