Immunogen sequence: ERPSETPPAP GVSWGPPPPG APVVISVKQE EGKQGRTGRR SHRAAPPCGF ARTRVCPPTF PGADAFPQ
Highest antigen sequence identity to the following orthologs: Mouse - 37%, Rat - 36%.
Members of the F-box protein family, such as FBXL22, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
蛋白别名: F-box and leucine-rich protein 22; F-box and leucine-rich repeat protein 22; F-box/LRR-repeat protein 22
基因别名: Fbl22; FBXL22
UniProt ID: (Human) Q6P050
Entrez Gene ID: (Human) 283807