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Invitrogen
FBXO33 Polyclonal Antibody
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FBXO33 Antibody (PA5-49503) in WB
Western blot analysis of FBXO33 in Mouse testis lysate. Samples were incubated with FBXO33 polyclonal antibody (Product # PA5-49503) using a dilution of 1:2,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Predicted band size: 63 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
产品信息
PA5-49503
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 416-449 amino acids from human FBXO33.
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AIG30-12-1; F-box only protein 33
基因别名: 5730501N20Rik; AI642135; BMND12; c14_5247; FBX33; FBXO33
UniProt ID: (Human) Q7Z6M2, (Mouse) Q8VE08
Entrez Gene ID: (Human) 254170, (Mouse) 70611
