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Proteintech
FBXO5 Polyclonal Antibody
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产品信息
10872-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FBXO5 Fusion Protein Ag1296 (1-447 aa encoded by BC018905)
偶联物
形式
Liquid
浓度
0.42 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSRRPCSCA LRPPRCSCSA SPSAVTAAGR PRPSDSCKEE SSTLSVKMKC DFNCNHVHSG LKLVKPDDIG RLVSYTPAYL EGSCKDCIKD YERLSCIGSP IVSPRIVELE TESKRLHNKE NQHVQQTLNS TNEIEALETS RLYEDSGYSS FSLQSGLSEH EEGSLLEENF GDSLQSCLLQ IQSPDQYPNK NLLPVLHFEK VVCSTLKKNA KRNPKVDREM LKEIIARGNF RLQNIIGRKM GLECVDILSE LFRRGLRHVL ATILAQLSDM DLINVSKVST TWKKILEDDK GAFQLYSKAI QRVTENNNKF SPHASTREYV MFRTPLASVQ KSAAQTSLKK DAQTKLSNQG DQKGSTYSRH NEFSEVAKTL KKNESLKACI RCNSPAKYDC YLQRATCKRE GCGFDYCTKC LCNYHTTKDC SDGKLLKASC KIGPLPGTKK SKKNLRRL (1-447 aa encoded by BC018905)
靶标信息
F-box proteins, critical components of the conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Early mitotic inhibitor 1; f-box only protein 31; F-box only protein 5; F-box protein Fbx5; fbxo5
基因别名: 2510044I10Rik; C85305; EMI1; FBX5; Fbxo31; FBXO5
UniProt ID: (Human) Q9UKT4, (Mouse) Q7TSG3
Entrez Gene ID: (Human) 26271, (Mouse) 67141, (Rat) 292263
oocyte maturation
cell cycle
spindle assembly involved in female meiosis I
mitotic nuclear division
regulation of mitotic cell cycle
vesicle organization
regulation of meiotic nuclear division
negative regulation of meiotic nuclear division
microtubule polymerization
spindle assembly
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle
positive regulation of meiosis I
obsolete inhibition of APC-Cdc20 complex activity
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
regulation of mitotic nuclear division
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
