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Invitrogen
FBXO6 Polyclonal Antibody
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产品信息
PA1-10884
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues 268-284 of human FBG2.
偶联物
形式
Liquid
浓度
1.6 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
RRID
产品详细信息
PA1-10884 detects FBG2 (F Box 2) in human, mouse,and rat samples.
PA1-10884 has been successfully used in Western blot procedures, where a band of approximately 34 kDa is detected.
PA1-10884 immunogen is a synthetic peptide corresponding to residues 268-284 of human FBG2.
靶标信息
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: F-box only protein 6; F-box only protein 6 b; F-box only protein 6b; F-box protein FBG2; F-box protein Fbx6; F-box protein that recognizes sugar chains 2; F-box/G-domain protein 2; FBG1; Fbs1; FBX2; NFB42; RP3-330O12.3
基因别名: AA408845; FBG2; FBS2; FBX6; Fbx6b; FBXO6; Fbxo6b
UniProt ID: (Human) Q9NRD1, (Rat) Q923V4, (Mouse) Q9QZN4
Entrez Gene ID: (Human) 26270, (Rat) 192351, (Mouse) 50762
DNA repair
glycoprotein catabolic process
response to unfolded protein
protein ubiquitination
ER-associated ubiquitin-dependent protein catabolic process
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
DNA damage checkpoint
protein polyubiquitination
proteolysis
