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Recommended positive controls: HL-60.
Predicted reactivity: Pig (83%), Rabbit (80%), Rhesus Monkey (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp686B08113; F-box only protein 7
基因别名: FBX; FBX07; FBX7; FBXO7; PARK15; PKPS
UniProt ID: (Human) Q9UF21
Entrez Gene ID: (Human) 25793