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Proteintech
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Immunogen sequence: PRGPTIKPCP PCKCPAPNLL GGPSVFIFPP KIKDVLMISL SPIVTCVVVD VSEDDPDVQI SWFVNNVEVH TAQTQTHRED YNSTLRVVSA LPIQHQDWMS GKEFKCKVNN KDLPAPIERT ISKPKGSVRA PQVYVLPPPE EEMTKKQVTL TCMVTDFMPE DIYVEWTNNG KTELNYKNTE PVLDSDGSYF MYSKLRVEKK NWVERNSYSC SVVHEGLHNH HTTKSFSRTP GK
The FC antibody fragment refers to a specific part of an antibody molecule, known as the fragment crystallizable region. It plays a crucial role in the immune response and has important functions in antibody-mediated immune reactions. The structure of the FC antibody fragment typically consists of the constant region of the antibody heavy chain. This region contains a specific amino acid sequence that allows the fragment to bind to various immune cells and molecules, such as Fc receptors and complement proteins. The FC fragment is responsible for initiating effector functions, such as antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement-dependent cytotoxicity (CDC). The FC antibody fragment acts as a bridge between the antibody and the immune system, facilitating the elimination of pathogens, infected cells, or other foreign substances. In addition to its immune functions, the FC region also plays a role in antibody stability and half-life. It can influence the pharmacokinetics and biodistribution of therapeutic antibodies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。