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Invitrogen
FCAR Polyclonal Antibody
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FCAR Antibody (PA5-121219) in WB
Western blot analysis of FCAR in extracts of 293T cells. Samples were incubated with FCAR Polyclonal antibody (Product # PA5-121219) followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
产品信息
PA5-121219
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 60-287 of human FCAR (NP_001991.1).
偶联物
形式
Liquid
浓度
1.66 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: 293T. The target is usually found in the following locations: Cell membrane, Secreted, Single-pass type I membrane protein.
Immunogen sequence: LMIIKNSTYR EIGRRLKFWN ETDPEFVIDH MDANKAGRYQ CQYRIGHYRF RYSDTLELVV TGLYGKPFLS ADRGLVLMPG ENISLTCSSA HIPFDRFSLA KEGELSLPQH QSGEHPANFS LGPVDLNVSG IYRCYGWYNR SPYLWSFPSN ALELVVTDSI HQDYTTQNLI RMAVAGLVLV ALLAILVENW HSHTALNKEA SADVAEPSWS QQMCQPGLTF ARTPSVCK
靶标信息
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD89; Fc alpha receptor; Fc fragment of IgA, receptor for; IgA Fc receptor; Immunoglobulin alpha Fc receptor
基因别名: CD89; CTB-61M7.2; FcalphaRI; FCAR
UniProt ID: (Human) Q1AJL9
Entrez Gene ID: (Human) 2204
