应用 | 建议稀释比 | 已发表文章 |
---|---|---|
流式细胞分析 (Flow) |
1:50-1:100 | - |
酶联免疫吸附实验 (ELISA) |
Assay-dependent | - |
免疫沉淀 (IP) |
Assay-dependent | - |
产品规格 | |
---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgG1 |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
MIP8a |
抗原 |
Recombinant soluble human Fc alpha R |
偶联物 |
Unconjugated
|
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
purified |
保存液 |
PBS |
内含物 |
0.09% sodium azide |
保存条件 |
4°C or -20°C if preferred |
RRID |
AB_2538336 |
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD89; Fc alpha receptor; Fc fragment of IgA, receptor for; IgA Fc receptor; Immunoglobulin alpha Fc receptor
基因别名: CD89; CTB-61M7.2; FcalphaRI; FCAR
UniProt ID: (Human) Q13603
Entrez Gene ID: (Human) 2204
分子生物学功能:
immunoglobulin receptor superfamily