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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: GVAPKAVLLL NPPWSTAFKG EKVALICSSI SHSLAQGDTY WYHDEKLLKI KHDKIQITEP GNYQCKTRGS SLSDAVHVEF SPDWLILQAL HPVFEGDNVI LRCQGKDNKN THQKVYYKDG KQLPNSYNLE KITVNSVSRD NSKYHCTAYR KFYILDIEVT SKP; Positive Samples: U-937, H460, 293T, HeLa, Mouse kidney; Cellular Location: Cell membrane, Single-pass type I membrane protein
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。