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Invitrogen
FDFT1 Recombinant Rabbit Monoclonal Antibody (4W10J4)
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FDFT1 Antibody (MA5-35552) in WB
Western blot analysis of FDFT1 in extracts of various cell lines. Samples were incubated with FDFT1 Monoclonal antibody (Product # MA5-35552) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-35552
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4W10J4
抗原
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SQS/FDFT1 (P37268)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.5 mg/mL
规格
150 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MGIGMAEFLD KHVTSEQEWD KYCHYVAGLV GIGLSRLFSA SEFEDPLVGE DTERANSMGL FLQKTNIIRD YLEDQQGGRE FWPQEVWSRY VKKLGDFAKP E
靶标信息
FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: farnesyl diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase 1; FPP:FPP farnesyltransferase; SQS; Squalene synthase; squalene synthetase; SS
基因别名: Erg9; FDFT1; SQS; SS
UniProt ID: (Rat) Q02769, (Mouse) P53798
Entrez Gene ID: (Rat) 29580, (Mouse) 14137
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